منابع مشابه
Immunoregulation in celiac disease
Celiac Disease (CD) is a T-cell mediated immune disease, in which gluten-derived peptides activate lamina propria effector CD4+ T cells. While these effector T cell subsets produce proinflammatory cytokines, which cause substantial tissue injury in vivo in CD, recent data suggest that additional subsets of CD4+ T cells exist with suppressor functions. These subsets include type 1 regulatory T c...
متن کاملDiagnostic Challenges in Celiac Disease
1. The most important challenge in diagnosis of celiac disease is not-performing the diagnostic tests in suspected persons. Because of multi-organ damage and multiple manifestations of disease, diagnosis of celiac disease may be delayed. It seems general physicians should be aware about uncommon presentations of disease and indications of celiac tests. 2. The second most important challenge is ...
متن کاملDiagnostic challenges in celiac disease
1-The most important challenge in diagnosis of celiac disease is not- performing the diagnostic tests in suspected persons. Because of multi-organ damage and multiple manifestations of disease, diagnosis of celiac disease may be delayed. It seems general physicians should be awared about uncommon presentations of disease and indications of celiac tests 2-The second most important challenge is...
متن کاملCeliac Disease
Celiac disease also known as gluten-sensitive enteropathy is characterized by intestinal mucosal damage and malabsorption from dietary intake of wheat, rye or barley. Symptoms may appear with introduction of cereal in the first 3 years of life. A second peak in symptoms occurs in adults during the third or forth decade and even as late as eight decade of life. The prevalence of this disease is ...
متن کاملAn Overview of Immunogenetic in Celiac Disease
Introduction: Celiac disease is an autoimmune disease caused by persistent intolerance to gluten, which is causedin people who are genetically predisposed. The disease presents with atrophy of the small intestinal mucosa and gastrointestinal and extra-gastrointestinal manifestations.Environmental factors like gluten and genetic factors such as HLA and non-HLA genes are involved in causing the d...
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ژورنال
عنوان ژورنال: Gastroenterology, Hepatology and Endoscopy
سال: 2016
ISSN: 2398-3116
DOI: 10.15761/ghe.1000103